Bacterial Apocalypse? Monday, Oct 15 2007
A challenge in making people care about techno-apocalypse is that most of the proposed technologies which could cause it exist in the future, not the present.
There’s all-out thermonuclear war, sure. If the Bush administration is dumb enough to attack Iran before he leaves office, then we could have serious problems with Russia (the country my family left when the Communists took over), whose minister of defense has cautioned the US not to lay a hand on Iran. If Putin’s successor is as gangster as he is, then Cold War part II (or Hot War part I) can’t be ruled out.
But would this kill everyone? Not too likely. Although burning cities do create black clouds which can initiate widespread crop failure, this effect is temporary. The world is a big place, and you can’t nuke it all.
So, in examining possible sources of human extinction risk, we have to look to the future. In a way this is reassuring, because we have time to prepare, but in another way it’s not, because some of the scenarios are too futuristic for people to take seriously.
I suppose the step after global thermonuclear war is genetically engineered plague. I’ve talked to four separate recombinant geneticists who say they would have a good chance at wiping out 90% of the human population in a decade if they had several million dollars and complete secrecy. (Their claims were more or less in tune even though they don’t know one other, to my knowledge.) Are they exaggerating? I don’t know, I’m not a biologist, but I think I’d rather err on the side of trusting them on this one.
What I do know about is history. The Black Death, which was possibly not the same thing as the bubonic plague, killed as much as half of Europe. Perhaps modern-day hygiene would prevent this from ever happening again, but the Spanish flu happened in conditions of nearly-modern hygiene, still killing 50-100 million, and spreading as far as the Arctic and remote Pacific islands (those are the two regions you need to watch if you care about extinction risk).
Would nuclear war threaten Tristan da Cunha, the most remote archipelago in the world? No. But a sufficiently powerful plague might. Especially a plague that spread to hundreds of millions of people before they started to display symptoms. Would such a thing be possible to genetically engineer? I’ve been talking with scientists about it since I got out of school but they often contradict each other, so I’m still confused.
My intuition tells me that when mankind can engineer something from scratch, it opens a vastly wider design space than nature alone could access. This is why humanity came up with computers, supersonic planes, and rocket ships, and the fastest swallow can’t even break the sound barrier. That’s why the Luddites got angry — because specialized looms could create textiles way faster than they ever could. Perhaps specialized microbes could kill people faster than any conventional weapon, or even nuclear weapons. I’d rather not watch it in action to find out.
I like thinking about the genetically engineered bacteria because it’s a happy medium in its future shock between thermonuclear war (which most accept as a possibility) and AI/robotics (which people have bizzare reactions to). There’s also nanowar, but that is also more futuristic.




btw: Putin successor is Putin. There will be puppet President and Putin will be Prime Minister with the real power. After a couple of terms it will be back to Putin as President.
It would be bomb Iran and not invade. Events look like it could easily turn into a big middle east regional mess. (not nuclear but a big regional conventional war.)
“If Putin’s successor is as gangster as he is,”
This happens to every global empire, without exception (so far as I can recall). I once talked to the Undersecretary-of-something-or-other under Condoleezza Rice, and when he mentioned the US invasion of Iraq, I pointed out that it violated international law (which it did; we tried and sentenced the Nazis at Nuremberg for “participation in a common plan or conspiracy for the accomplishment of crime against peace” and “planning, initiating and waging wars of aggression and other crimes against peace”). He replied that international law didn’t really mean anything, because there was nobody to enforce it and therefore “might makes right”.
I’m not sure that a sufficiently large nuclear exchange wouldn’t pose an existential risk. Are there recent nuclear winter models (apart from those for South Asian regional wars) that include effects on carbon cycle? As for bio, a determined misanthrope could release more than one pathogen, sequentially, to increase the probability of extinction. Would be useful to elicit subjective probabilities of various extinction events from large number of experts in relevant fields — infectious disease, MNT, AI, climate, astronomy, etc.
I used to be a biologist, and back when I was one I thought that with a few million dollars of funding and a few years I would be able, if I wanted to, to build pathogens that could kill 90% of the world population. Later I did a lot more thinking about existential risk, public health, epidemiology, etc, and concluded that I had been mistaken for reasons that were not obvious when working with a standard biological conceptual tool kit.
The Spanish Flu happened immediately after WWI, and 90 years ago. This is a far cry from nearly modern conditions unless you mean near to modern Africa. Western life expectancies back then were about 51 years (ignoring the effects of WWI, the flu, and the viral encephalitis epidemic).
I agree that sufficiently advanced biology might be capable of doing terrible things with bacteria, but by the time it can, nanotech, even of the non-molecular variety, will probably be able to counter those terrible things, even if molecular nanotech doesn’t make bacteria the least of our problems, which I would expect to happen sooner in any event.
Personally I am acutely worried about oil depletion and the potential for a hard economic crash. No more oil will mean no more largescale industrial agriculture, which automatically implies a die-off of maybe as much as a billion people in the third world. Die off directly through starvation, but also through flaring resource wars, migrations, diseases and general collapse of infrastructure.
The most distressing idea is that IF we have an economic collapse due to oil depletion, the superpowers might become tempted to spread a handful of mutually-complementing diseases. One highly vectored disease is plausible to defend your country against; 5 or more weaponized diseases and your CDC will be stuck in Quixote-mode. Plus it will kill off the weak, nonproductive (old people) and will hit especially hard in the thirdworld. It would be an ideal solution to pacify a global flare-up of resource wars, and it will instantly cut down international traffic and (!) oil consumption.
And so what if your own population suffers 5% casualties? As long as the other sides lose more, it would be a strategic benefit.
Am I a cynic to even contemplate such an evil idea? Or do I think like the bastards in control?
I generally agree that the threat from new forms of biology is more serious than other possible dangers. Crazy AIs, or the conventional nuclear threat are relatively sexy high tech doomsday scenarios whereas the humble virus or bacteria is much harder to get into the media headlines.
One scenario which I havn’t heard anyone talking about would be counter-adaptations by natural microorganisms in response to the introduction of new synthetic or genetically engineered life forms. There are good reasons for genetic engineering plants and animals to produce increased yields and so on. But no creatures live in isolation and nature is full of escalating arms races and balances of power. The introduction of new genetic strains could force microorganisms associated with these to adopt new and unexpected survival strategies, so of which could be deleterious to humans.
The biggest threat as far as I can see would be some sort of attack on the most fundamental life forms in the ecosystem upon which everything else depends, such as soil bacteria.
“No more oil will mean no more largescale industrial agriculture,”
Agriculture is something like 4% of US GDP. We can keep it going with Fischer-Tropsch if we have to, and it’ll be one of the very last things to cut- we all have to eat, after all.
“The introduction of new genetic strains could force microorganisms associated with these to adopt new and unexpected survival strategies, so of which could be deleterious to humans.”
Law of Microbial Infallibility: There is a microbe somewhere which can break down every possible biologically produced substance. Pretty much every niche has already been filled, and we aren’t extinct yet.
“Agriculture is something like 4% of US GDP. We can keep it going with Fischer-Tropsch if we have to, and it’ll be one of the very last things to cut- we all have to eat, after all.”
Sure, you said US. A billion chinese could care less about the US. Try the same model on most of the third world, and please incorporate more than a hundred cities in the third world with MILLIONS of people living in each such city !!! Take Brazil. Sao Paolo. Imagine agriculture collapsing in that region because they cant afford oil. Hundreds of millions of people without food. All of those people fleeing to the US, Europe, Japan, Australia, Russia, where there still IS food. Walking. In Boats. In Coal-driven buses. On the run for wars, diseases, famine, crime.
Tom, your law applies well to systems where gradual adaptation is possible. But we regularly see invasive species extinguish native species because of sudden introduction. I think the release of multiple microbes engineered to disrupt core biological/ecological processes poses an existential risk, though it’s hard to estimate the magnitude of this risk relative to others. Michael V, can you elaborate on the nanotechnologies you believe will emerge in time to reduce near-term risks from synthetic biology? And do synthetic viruses not qualify as “nanotech risks”?
I don’t think so, be can already have a bacterial apocalypse with natural bacteria we already know.